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The basic symptom is tiredness, but as so many people suffer from tiredness (up to a third of the population at any one time) tiredness alone is not sufficient for the diagnosis. By present definition, someone must have been tired for at least six months and unable to work or to deal with domestic and social activities. Often people have brief periods of apparent normality when they can go out and are active but these seem to be followed by several days of worse than usual tiredness. Pains in the muscles anddepression are also common accompanying features.

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